Rat Range
Introduction
Following advancements with knockout rats in 2003 and an increasing number of available inbred rat models, the rat has re-emerged as an excellent platform on which to build the genetic and genomic resources and tools to delineate the connections between genes and biology.
Rats have routinely been used as models in conditions ranging from cardiovascular diseases through to autoimmune diseases. However in some cases specific aspects of human disease are only summarized in rat making these animals an excellent resource for studying and identifying genetic pathways relevant to human disease (e.g. hypertension).
For your research AbD Serotec offers an extensive rat range of reagents. The range includes a wide choice of clones, formats and conjugates – including Alexa Fluor ® 405, 488, 647 and 700 fluorochromes, plus our new tandem conjugates and dual-color reagents.
Featured Products
Widest range of OX clones available
AbD Serotec marketed their first OX mAb in 1985 and since then has gone from strength to strength with over 50 OX clones now appearing in the 2007 Antibody Resource Book. These OX clones have been invaluable for many important research breakthroughs, with antibodies such as MCA275 (OX-42) being renowned as the most reliable neurological marker for rat microglia.
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Dual-color reagents for flow cytometry
AbD Serotec offers a range of dual-color reagents to assist you in your detection of rat leukocytes by flow cytometry. These reagents are an excellent tool for the identification of T cells (mature, helper, cytotoxic and activated) and B cells.
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ED clone range for studying macrophages
AbD Serotec is the primary source of the ED clones, which are a comprehensive range of reagents for the study of rat macrophages. These antibodies have a wide range of applications and can be used in immunohistochemistry. Of particular note is MCA341 anti-CD68 (ED1), which is the most reliable rat macrophage marker.
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Literature Download
Antibodies to Rodent Dendritic Cells & Macrophages
Please click here for a poster detailing our key rat and mouse antibodies for detecting dendritic cells (DCs) and macrophages.
Antibodies Useful for Studying Regulatory T cell Biology
Please click here for our extensive range of antibodies to Treg markers and related molecules for the rat, mouse and human ranges.
Alexa Fluor® is a registered trademark of Molecular Probes Inc, OR, USA
